NAME KHALDOUN SHARIF
DATE OF BIRTH 7th September 1961

SOCIAL STATUS Married

NATIONALITY Jordanian/ British

CORRESPONDENCE E-mail: khaldoun@btinternet.com
Fax: 00-44-121-627 2701

CURRENT APPOINTMENT
Consultant Obstetrician and Gynaecologist,
Director of Assisted Conception Services,
Birmingham Women's Hospital;
Honorary Senior Lecturer in Obstetrics & Gynaecology,
Faculty of Medicine, The University of Birmingham,
Birmingham, United Kingdom

MEDICAL QUALIFICATIONS
1985 M.B.B.Ch. (Hons.) Ain-Shams University, Cairo, Egypt.
1991 M.R.C.O.G. Royal College of Obstetricians & Gynaecologists, London, UK.
1993 M.F.F.P. Faculty of Family Planning, London, UK.
1997 C.C.S.T. Specialist Training Authority, London, UK.
1999 M.D. Birmingham University, Birmingham, UK.

PRIZES & AWARDS
International Society of Ultrasound in Obstetrics & Gynaecology, 1995-France: ISUOG Prize of the 'Interventional Ultrasound in Obstetrics & Gynaecology' meeting in Clermont-Ferrand, France, awarded for the presentation of the paper on "US-guided transmyometrial embryo transfer".
University of Birmingham, 1995-UK: Scientific Projects Committee Award, for work on embryo transfer presented at the 1995 international annual meeting of the Egyptian Fertility Society, Cairo.
Royal College of Obstetricians & Gynaecologists, 1994-UK: RCOG Travel Award, for work on embryo transfer presented at The Jones Institute for Reproductive Medicine, Eastern Virginia Medical School, Norfolk, Virginia (November, 1994).

REGISTRATION & ACCREDITATION
Full registration with the General Medical Council, number 3602072, on the specialist register.
Certificate of Completion of Specialist Training in obstetrics & gynaecology awarded on 1st May 1997.
PROFESSIONAL MEMBERSHIPS
British Fertility Society.
Medical Protection Society.
British Medical Association.
International College of Surgeons.
British Medical Ultrasound Society.
American Society for Reproductive Medicine.
Association of the Study of Medical Education.
Medical Writers' Group of the Society of Authors.

CLINICAL EXPERIENCE
GENERAL OBSTETRICS & GYNAECOLOGY
I have received all my postgraduate training in the UK. I had thorough training and wide experience in all aspects of routine, high risk and operative obstetrics. Gynaecologically, besides my special interest in reproductive medicine, I have wide experience in general gynaecology, both medically and surgically. In my current job, besides my work in reproductive medicine, I have weakly commitments to obstetric and gynaecology in- and out-patients as well as general gynaecology operating lists.

REPRODUCTIVE MEDICINE
My subspecialist interest is reproductive medicine. I am experienced in all aspects of reproductive medicine and surgery, as well as infertility-related diagnostic and interventional radiology and ultrasound. My experience includes infertility counselling and work-up, ovulation induction, intrauterine insemination, in-vitro fertilisation (IVF), intracytoplasmic sperm injection (ICSI), gamete donation and tubal reconstructive microsurgery.

I am currently the Director of Assisted Conception Services at the Birmingham Women's Hospital, a tertiary referral centre in Central England, serving a population base of 6 million and receiving over 1000 referrals in reproductive medicine per annum. I have special interest and expertise in setting up new infertility units and in fact I was responsible for the setting-up, organisation, and running of the clinical aspects of the first IVF unit in the University of Birmingham back in 1994.

MALE INFERTILITY
I am the chief clinician in charge of male factor infertility at the Assisted Conception Unit. I am experienced in the investigation and treatment of male factor, including performing PESA (percutaneous epididymal sperm aspiration), TESA (testicular sperm aspiration), and TESE (testicular sperm extraction) as well as open testicular biopsy under both general or local anaesthesia. I am also experienced in the clinical and genetic aspects of ICSI (intracytoplasmic sperm injection).

MINIMAL ACCESS SURGERY
I am experienced in performing diagnostic and operative hysteroscopy and laparoscopy for infertility-related disorders, and have level 3 RCOG-endoscopy accreditation.
My experience in operative hysteroscopy includes laser resection of uterine septum, submucous fibroids and intrauterine synechiae as well as tubal catheterisation. In operative laparoscopy I am experienced in ovarian biopsy, laser adhesiolysis, ovarian drilling, and laparoscopic treatment of ectopic pregnancy. I am also experienced in out-patient hysteroscopy.

IMAGING EXPERIENCE
I have special expertise in performing selective salpingography under x ray control for the diagnosis and treatment of proximal tubal occlusion.
I am also experienced in performing both diagnostic and interventional ultrasound scanning in obstetrics and gynaecology. In gynaecology and reproductive medicine I am experienced in diagnostic sonography as well as ultrasound-directed egg-collection, embryo-transfer and pelvic cyst drainage. In obstetrics my experience includes early pregnancy assessment, antenatal booking scans, fetal biometry, Doppler flow imaging, biophysical profile scoring and amniocentesis.

OPERATIVE EXPERIENCE
I am a competent abdominal and vaginal surgeon and have wide surgical experience in performing general gynaecological operations as well as reproductive surgery. I am also experienced in radical pelvic surgery for benign conditions such as surgery for frozen pelvis, extensive endometriosis and pelvic adhesions.
In obstetrics, I also have wide experience in instrumental and operative deliveries. This includes management of rupture uterus and caesarean hysterectomy.

TEACHING EXPERIENCE

UNDERGRADUATE TEACHING EXPERIENCE
As a University Senior Lecturer, I am responsible for both formal and informal 5th year medical students teaching in Obstetrics and Gynaecology. I also lecture to the 2nd year students on the Anatomy and Physiology; Endocrinology; and Law and Ethics modules.

POSTGRADUATE TEACHING EXPERIENCE
Postgraduate teaching is the part of my job I enjoy most and consider it the logical extension of medical training, research and practice. I have taken a particular interest in training for the MRCOG, and have so far published 4 books in this area, and they are on the RCOG recommended reading list. Twice-a-year I organise a Part 2 MRCOG written course and an OSCE course at the Birmingham Women's Hospital. I also lecture on the Birmingham theoretical MRCOG 2 Course, and have been invited regularly to lecture at the MRCOG Courses at the Royal College of Obstetricians and Gynaecologists, London; Keele University, Stoke; Saudi Arabia; Egypt; and Trinidad.

MD THESIS
I have a "Doctor of Medicine" degree from the University of Birmingham (1999), and the results from my thesis have been published in papers in international peer-reviewed journals.
The hypothesis tested in this thesis was that the simplification of various IVF steps is consistent with successful outcome. The chances of success with IVF are related to the number of attempts the couple has. However, the cost and complexity of various IVF procedure and monitoring techniques limit the number of attempts any particular couple undergoes, thus reducing the chances of success. Simplification of IVF will encourage more couples to undergo more attempts and hence increase the overall chances of success.

MANAGEMENT EXPERIENCE
I believe that management skills are as necessary as clinical skills in successfully running any medical establishment. I participate actively and fully in the management of the ACU, including budgetary planning, inter-departmental coordination, management of staff and patients' complaints management.

COMMITTEES' MEMBERSHIP
Executive Council, Arab Medical Association (UK and Ireland).
Examination Committee, Arab Board of Obstetrics and Gynaecology, Damascus (1998).
Information Technology Committee, Medical School, University of Birmingham (1997/1998).
RCOG Trainees Committee, West Midlands Region (1996/1997).

Ad Hoc PROFESSIONAL ACTIVITIES
Special Advisor - National Gamete Donation Trust (NGDT), UK.
Referee - 'Fertility and Sterility', 'Human Reproduction', 'British Journal of Obstetrics and Gynaecology' and 'Middle East Fertility Society Journal'.
Chairman of Scientific Sessions - 'RCOG Senior Staff Conference, 1999', 'RCOG Specialist Registrars Conference, 1999', 'Egyptian Fertility Society Annual Meetings, 1998 and 1999'.
PUBLICATIONS
Books :
· Sharif K, Weaver JB (2000) MRCOG Survival Guide - Second Edition. WB Saunders, London .
· Sharif K (2000) Oral Assessment Examination for the MRCOG. WB Saunders, London [in press].
· Sharif K, Jordan JA (Editors) (1997) Clinical Obstetrics & Gynaecology: MCQ for MRCOG Part 2. WB Saunders, London. Published also in interactive computer disk format.
· Sharif K, Gee H, Whittle MJ (1995) Basic Science in Obstetrics & Gynaecology: MCQ for MRCOG Part 1. WB Saunders, London. Published also in interactive computer disk format.
Chapters :
· Sharif K (2000) Advances in the treatment of male factor infertility, In: Recent Advances in Obstetrics & Gynaecology (Ed. J.Bonnar), volume 21, Churchill Livingston, Edinburgh141-159.
· Watson E, Sharif K (2000) Shoulder Dystocia, In: RCOG Year Book of Obstetrics & Gynaecology (Ed. D.Sturdee), RCOG, London, [in press].
· Gee H, Sharif K (1998) Management of the first stage of labour, In: Vignettes for the MRCOG (Ed. R G Farquharson), Quay Books, Wiltshire, pp 89-103.
· Sharif K, Afnan M (1997) Ovarian Function and Ovulation Induction, In: Gynaecology (Eds. R.Shaw, P.Soutter, S.Stanton), 2nd edition, Churchill Livingston, Edinburgh, pp 223-236.

Papers:
· Sharif K (2000) Reclassification of azoospermia: the time has come? Human Reproduction 15, 237-238.
· Lashen H, Afnan M, Sharif K (1999) A controlled comparison of ovarian response to controlled stimulation in first generation Asian women compared with white Caucasians undergoing in vitro fertilisation. British Journal of Obstetrics & Gynaecology 106, 407-409.
· Sharif K, Elgendy M, Lashen H, Afnan M (1998) Age and basal FSH as predictors of IVF outcome. British Journal of Obstetrics & Gynaecology 105, 107-112.
· Sharif K, Afnan M (1998) Quality control in postgraduate training. British Medical Journal 316, 7142S, 2-3.
· Sharif K, Afnan M, Lashen H, Elgendy M, Morgan C, Sinclair L (1998) Is bed rest necessary following embryo transfer? Fertility and Sterility 69, 478-481.
· Sinclair L, Morgan C, Lashen H, Afnan M, Sharif K (1998) Nurses performing embryo transfer. The Birmingham experience. Human Reproduction 13, 699-702.

· Elgendy M, Afifi Y, Lenton W, Afnan M , Sharif K (1998) Reducing the dose of GnRHa on starting ovarian stimulation; effect on ovarian response and IVF outcome. Human Reproduction 13, 2382-2385.
· Sharif K, Kato O (1998) Technique of transmyometrial embryo transfer. Middle East Fertility Society Journal 2, 124-129.
· Lashen H, Afnan M, Sharif K, Afifi Y, Elgendy M (1998) Manipulating the gonadotrophin dose in controlled ovarian hyperstimulation for IVF and its effects on ovarian response. Egyptian Journal of Fertility and Sterility 2, 31-36.
· Sharif K, Afnan M, Khalaf Y, Bilalis D, Lashen H (1997) Ultrasound prediction of follicular volume in assisted conception. Middle East Fertility Society Journal 2, 53-56.
· Sharif K, Afnan M, Lenton W, Bilalis D, Hunjan M, Khalaf Y (1996) Transmyometrial embryo transfer following difficult immediate mock transcervical transfer. Fertility and Sterility 65, 1071-1074.
· Gray D, Sharif K (1996) Home birth: is it a safe option? British Journal of Midwifery 4, 144-146.
· Sharif K, Afnan M, Lenton W, Khalaf Y, Ebbiary N, Bilalis D (1995) Do patients need to remain in bed after embryo transfer? The Birmingham experience of 103 IVF cycles with no bed rest following embryo transfer. Human Reproduction 10, 1427-1429.
· Sharif K, Weaver JB, Afnan M, Newton JR (1995) How to organise a local revision course for postgraduate examinations. British Journal of Hospital Medicine 53, 131-135.
· Sharif K, Jordan JA (1995) The six week postnatal visit: are we doing it right? British Journal of Hospital Medicine 54, 7-10.
· Gee H, Sharif K (1994) Management of the first stage of labour. British Journal of Hospital Medicine 52, 395-400.
· Sharif K, Barrett P, Sharma V (1993) Subcutaneous versus intramuscular self-administration of highly purified urofollitrophin in superovulation for in vitro fertilisation: a randomised, cross-over study of patients' preferences and tolerability. British Journal of Clinical Research 4,183-189.
· Sharif K, Clarke P, Whittle MJ (1993) Routine six-week postnatal vaginal examination: to do or not to do? Journal of Obstetrics & Gynaecology 13, 251-252.
· Sharif K, Whittle MJ (1993) Routine antenatal fetal heart auscultation: is it necessary ? Journal of Obstetrics & Gynaecology 13, 111-112.
· Sharif K, Olah K, Gee H (1993) Umbilical cord blood pH and base deficit: time dependent change at room temperature. Journal of Obstetrics & Gynaecology 13, 107-110.

Case Reports:
· Kaufmann S, Sharif K, Sharma V, McVerry B (1998) Term delivery in a woman with severe congenital neutropaenia treated with growth colony stimulating factor. Human Reproduction 13, 498-499.
· Sharif K, Kaufmann S, Sharma V (1994) Heterotopic pregnancy obtained after in-vitro fertilisation and embryo transfer following bilateral total salpingectomy. Human Reproduction 9, 1966-1967.
· Sharif K, Gee H, Bombiari L (1993) Pelvic inflammatory disease in pregnancy. Journal of Obstetrics & Gynaecology 13, 38-39.
· Sharif K, Mould J (1993) Paraplegia: an unusual presentation of endometrial carcinoma. Obstetrics & Gynaecology Today 4, 35-36.
· Sharif K, Gee H (1993) Combined intrauterine and extrauterine gestations. Obstetrics & Gynaecology Today 4, 15.
Correspondence:
· Sharif K (1998) Bed rest following embryo transfer-Necessary? Fertility and Sterility 70, 982.
· Sharif K, Lenton W, Bilalis D, Afnan M (1996) Techniques of embryo transfer. Human Reproduction 11, 458-459.
· Sharif K (1994) The role of ergometrine in the development of pulmonary oedema with b agonists in preterm labour. British Medical Journal 308, 721.
· Sharif K, Sharma V (1994) Ectopic pregnancy: are biochemical tests at all helpful? British Journal of Obstetrics& Gynaecology 101, 179-180.
· Sharif K, Hammadieh N (1993) Routine postnatal pelvimetry: forget it. British Medical Journal 307, 1065.
· Sharif K (1993) Delayed analysis of umbilical cord blood. Journal of Obstetrics& Gynaecology 13, 387.
· Sharif K, Gee H (1992) Emergency cervical cerclage. British Journal of Obstetrics& Gynaecology 99, 529.
· Sharif K (1991) Fetal heart rate monitoring in labour. Hospital Doctor 3,12.
· Sharif K (1991) Patient's access to medical records. Hospital Doctor 22,10.
Posters:
· Sharif K, Afnan M, Yassen I, Awanouga, N (1999) High dose stimulation for IVF in young patients with high basal FSH. Presented at the Toronto annual meeting of the American Society for Reproductive Medicine.

· Sharif K, Afnan M, Elgendy M, Yassen I (1998) High dose stimulation for patients with high basal FSH in IVF. Presented at the Amman 5th meeting of the Middle East Fertility Society.
· Lashen H, Afnan M, Bilalis D, Sharif K (1997) Embryo cryopreservation to prevent OHSS; a better outcome for patients. Presented at the Edinburgh meeting of ESHRE.
· Lashen H, Afnan M, Elgendy M, Bilalis D, Sharif K (1997) Measuring LH levels on hCG day can predict IVF outcome. Presented at the Edinburgh meeting of ESHRE.
· Elgendy M, Afnan M, D'Archy Y, Gibbs A, Lashen H, Lenton W, Sharif K (1997) The minimal effective dose of GnRH analogue for controlled ovarian hyperstimulation in IVF. Presented at the Edinburgh meeting of ESHRE.
· Sharif K, Bilalis D, Lenton W, Hunjan M, Afnan M (1995) Pregnancy rates after elective and obligatory transfer of 2 embryos. Presented at the Warwick joint meeting of the British Andrology Society & British Fertility Society.
· Sharif K, Bilalis D, Khalaf Y, Lenton W, Hunjan M, Afnan M (1995) The ultrasound prediction of follicular volume. Presented at the Warwick joint meeting of the British Andrology Society & British Fertility Society.
· Sharif K, Khalaf Y, Bilalis D, Bhattacharya D, Afnan M (1995) The simplification of the methotrexate treatment of ectopic pregnancy: oral folinic acid rescue. Presented at the Warwick joint meeting of the British Andrology Society & British Fertility Society.
· Sharif K, Lenton W, Bilalis D, Khalaf Y, Hunjan M, Afnan M (1995) Ultrasound-directed transvaginal transmyometrial embryo transfer. Presented at the Warwick joint meeting of the British Andrology Society & British Fertility Society.
· Khalaf Y, Sharif K, Bilalis D, Lenton W, Hunjan M, Afnan M (1995) The correlation between collected oocyte number and quality in IVF-ET. Presented at the Warwick joint meeting of the British Andrology Society & British Fertility Society.
· Morgan C, Sinclair L, Sharif K, Bilalis D, Afnan M (1995) The effect of structured educational intervention on the chosen number of transferred embryos after IVF. Presented at the Warwick joint meeting of the British Andrology Society & British Fertility Society.
· Afnan M, Sharif K (1995) Tubal catheterisation in the treatment of proximal tubal occlusion. Presented at the Dublin 27th British Congress of Obstetrics & Gynaecology.
· Ahmed N, D'Archy Y, Gibb A, Afnan M, Sharif K, Newton JR (1995) Effect of antisperm antibodies on semen characteristics before and after swim-up preparation. Presented at the Washington 51st meeting of the American Society of Reproductive Medicine.
· Sharif K, Barrett P, Wiley M, Haigh C, Sharma V (1993) Self administration of a new highly purified urofollitrophin; analysis of efficacy and patient preference for route of administration. Presented at the Oxford annual meeting of the British Fertility Society.

Oral Presentations:
· Sharif K, Afnan M, Yassen I, Awanouga, N (1999) Evaluation of endometrial thickness and vaginal bleeding as predictors of pituitary desensitisation using long protocol gonadotrophin-releasing hormone agonists. Presented at the Toronto annual meeting of the American Society for Reproductive Medicine.
· Sharif K, Kato O (1998) Technique and results of transmyometrial embryo transfer. Presented at the Amman 5th meeting of the Middle East Fertility Society.
· Lashen H, Afnan M, Kennefik A, Haskins J, Sharif K (1998) Optimisation of the outcome in donor insemination programme. Presented at the Goteborg meeting of the ESHRE.
· Lashen H, Afnan M, Sharif K, Afifi Y, Elgendy M (1998) Ethnic origin and in-vitro fertilisation. Presented at the Sheffield meeting of the British Fertility Society.
· Lashen H, Afnan M, McDougall L, Sharif K (1998) Optimisation of controlled ovarian stimulation for intrauterine insemination. To be presented at the San Francisco joint meeting of the American Society of Reproductive Medicine & IFFS.
· Elgendy M, Afnan M, Afifi Y, Sharif K (1998) A prospective randomised trial assessing a step-down dose versus a fixed dose regimens of recombinant FSH for controlled ovarian hyperstimulation in IVF/ICSI programs. To be presented at the San Francisco joint meeting of the American Society of Reproductive Medicine & IFFS.
· Sharif K, Afnan M (1996) The medical management of ectopic pregnancy. Presented at the 2nd Pan Italian-Arab Conference in Obstetrics and Gynaecology, Amman, Jordan.
· Sharif K, Lenton W, Afnan M (1995) Ultrasound directed transvaginal transmyometrial embryo transfer following IVF. Presented at the Clermond-Ferrand/ France meeting on Interventional Ultrasound in Obstetrics and Gynaecology (awarded ISUOG Prize).
· Afnan M, Sharif K (1995) A new approach to the classification of proximal tubal disease. Presented at the Washington 51st meeting of the American Society of Gyne-Radiology.
· Afnan M, Sharif K, McHugo J (1995) Correlation of intrauterine pregnancies following tubal catheterisation and tubal filling pressures. Presented at the Washington 51st meeting of the American Society of Gyne-Radiology.
· Afnan M, Sharif K(1995) Evaluation of a commercially available tubal filling pressure measuring system. Presented at the Washington 51st meeting of the American Society of Gyne-Radiology.
· Afnan M, Sharif K (1995) The place of standardised selective salpingography in the diagnosis and treatment of tubal disease. Presented at the London 4th biennial meeting of the International Society for Gynaecologic Endoscopy.


INVITED LECTURES
· Where Next in Assisted Conception. Presented at the Specialist Registrars Meeting of the Royal College of Obstetricians & Gynaecologists, London, 16th September 1999.
· Advances in the management of male factor infertility. Presented at the Birmingham Meeting of the RCOG Visiting Club, Birmingham University, Birmingham, 19th March 1999.
· The medical management of ectopic pregnancy. Presented at the Welsh Institute of Minimal Access Therapy (WIMAT), Cardiff University, Cardiff, 1st May 1998.
· Transmyometrial embryo transfer: The Birmingham Experience. Presented at the Transmyometrial Embryo Transfer Workshop, Schoysman Fertility Foundation, van Helmont Hospital, Vilvoorde, Belgium, 8th November 1997.
· Techniques of Transmyometrial embryo transfer. Presented at the Transmyometrial Embryo Transfer Workshop, Schoysman Fertility Foundation, van Helmont Hospital, Vilvoorde, Belgium, 8th November 1997.
· Who should do embryo transfer? Presented at the Embryo Transfer Symposium, University of Stockholm, Stockholm, Sweden, 6th September 1997.
· The modern management of ectopic pregnancy. Presented at the second international meeting of the Egyptian Fertility & Sterility Society, Cairo, 2nd September 1996.
· The management of infertility in primary care. Presented at the annual meeting of the Faculty of Family Planning and Reproductive Health Care, Regent's College, London, 31st May 1996.
· The end of difficult embryo transfer. Presented at the first international meeting of the Egyptian Fertility & Sterility Society, Cairo, 11th September 1995.
· New changes in the MRCOG examination. Presented at the Royal College of Obstetricians & Gynaecologists, London, 5th July 1995.
· How to pass the MRCOG. Presented at the Royal College of Obstetricians & Gynaecologists, London, 23rd January 1995.